Nasopharyngeal (nay-zoh-fuh-RIN-jee-ul) carcinoma ndi khansa yomwe imapezeka mu nasopharynx, yomwe ili kumbuyo kwa mphuno yanu ndi kuseri kwa mmero wanu.
Nasopharyngeal carcinoma ndi yosowa ku United States.Zimapezeka kawirikawiri m'madera ena a dziko lapansi - makamaka Southeast Asia.
Nasopharyngeal carcinoma ndizovuta kuzindikira msanga.Mwina ndi chifukwa chakuti nasopharynx ndizovuta kufufuza ndipo zizindikiro za nasopharyngeal carcinoma zimafanana ndi zina, zofala kwambiri.
Nasopharyngeal carcinoma nthawi zambiri imapezeka mwa anthu azaka zapakati komanso okalamba opitilira zaka 40, ndipo imakhala ndi mawonekedwe amdera komanso achibale awo, ndipo kuchuluka kwa anthu ku Guangdong kumayambira ku China, komwe kumatchedwanso "cancer ya Guangdong".
1.Malangizo Othandizira Kuzindikira ndi Kuchiza kwa Nasopharyngeal carcinoma
Mu 2021 Guidelines for the Diagnosis and Treatment of Nasopharyngeal Carcinoma, Chinese Society of Clinical Oncology(CSCO) inaphatikizapo njira zodziwira serological mu Class I umboni wa matenda a nasopharyngeal carcinoma, ndipo adanena kuti kuphatikiza kwa EB-VCA-IgA. ndi ma EB-NA1-IgA EB-virus a EB amatha kuonjezera kuchuluka kwa matenda a nasopharyngeal carcinoma ndi katatu (21% ~ 79%) ndikuchepetsa chiopsezo cha imfa ndi 88%!The 2019 Expert Consensus on the Clinical Application of Markers for Nasopharyngeal Carcinoma adanenanso kuti EBV-EA-IgA ndi chizindikiro cha matenda a EBV aposachedwa kapena kufalikira kwamphamvu kwa EBV, motsimikizika kwambiri, ndipo nthawi zambiri amagwiritsidwa ntchito powunika khansa ya nasopharyngeal. ndi kuzindikira msanga.
Kafukufukuyu akuwonetsa kuti kuzindikirika katatu kophatikizana kwa EBV-VCA-IGA, EBV-EA-IGA ndi EB-NA1-IgA kuphimba kwathunthu mawonekedwe amtundu wa EBV, komwe kumathandizira kuzindikira komanso kutsimikizika kwa nasopharyngeal carcinoma kuzindikira, kumachepetsa kuzindikirika kophonya, kumatsimikizira kulondola kwa kuneneratu kwa matenda, ndikulosera za matenda azaka 5-10 pasadakhale, omwe ali oyenera kuyezetsa khansa ya nasopharyngeal.
2.VCA-IgA+EA-IgA+NA1-IgA yopangidwa ndi Beijing Beier ikhoza kupereka njira yodziwira matenda oyambirira a Nasopharyngeal Carcinoma.
Magnetism particulate immuno chemistry luminescence njira
| Dzina lazogulitsa | Chidule |
| EB kachilombo ka VCA-IgA antibody kuzindikira zida | EB-VCA-IgA |
| EB virus EA-IgA antibody kuzindikira zida | EB-EA-IgA |
| EB kachilombo ka NA1-IgA antibody kuzindikira zida | EB-NA1-IgA |
Elisa Njira:
| Dzina lazogulitsa | Chidule |
| EB virus VCA-IgA Elisa zida | EB-VCA-IgA |
| EB virus EA-IgA Elisa zida | EB-EA-IgA |
| EB virus NA1-IgA Elisa zida | EB-NA1-IgA |
3.Magwiridwe Azinthu
Zida zoyesera za VCA-IgA zopangidwa ndi Beijing Beier zitha kulowa m'malo mwa zida za EU kuti azindikire msanga ndikuwunika khansa ya nasopharyngeal.
British Medical Journal (BMJ) (impact factor 16.378) ndi Imodzi mwa magazini anayi otsogola padziko lonse lapansi azachipatala.Mu 2017, gulu lofufuza lidasindikiza pepala mu British Medical Journal (BMJ) "Kuwunika kwa zida zisanu ndi ziwiri zophatikizananso za VCA-IgA ELISA za matenda a nasopharyngeal carcinoma ku China: mayeso owongolera milandu".
Mu pepala ili, odwala 200 omwe ali ndi nasopharyngeal carcinoma (NPC) ndi 200 yachibadwa ya seramu ya anthu (SYSUCC) ochokera ku Sun Yat-sen University Cancer Center adaphunzira ndikuyesedwa, komanso machitidwe a EB-VCA-IgA (ELISA) opangidwa ndi 8. opanga mtunduwu pamsika wapakhomo adafaniziridwa pakuwunika magwiridwe antchito.Mapeto ake ndikuti zida za EBV-VCA-IgA (ELISA) zopangidwa ndi Beijing Beier zili ndi zotsatira zofananira ndi EBV-VCA-IgA (ELISA) zopangidwa ndi reagent yochokera kunja Oumeng, ndi EBV-VCA-IgA (ELISA) zida zopangidwa ndi Beijing Beier zitha kulowa m'malo mwa zida zomwe zatumizidwa kunja kuti zizindikire msanga komanso kuwunika kwa nasopharyngeal carcinoma.Zambiri za opanga mtunduwu omwe atenga nawo gawo pamayeso akuwonetsedwa mu Gulu 1, zotsatira za mayeso zikuwonetsedwa mu Gulu 2, ndipo zotsatira zake zikuwonetsedwa mu Gulu 3.
Mapeto a Mayeso
Zida zitatu zophatikizananso za VCA-IgA-BB,HA ndi KSB- zinali ndi zotsatira zowunikira zofanana ndi zida zokhazikika.Atha kulowetsedwa m'malo mwa zida zokhazikika ndipo kuphatikiza kwawo kungagwiritsidwe ntchito pozindikira koyambirira ndi kuwunika kwa NPC.
Nthawi yotumiza: Feb-23-2023